IOM/FDA/CDC doctors: Food proteins present in vaccines cause the development of food allergies

IOM/FDA/CDC doctors: Food proteins present in vaccines cause the development of food
allergies
Nobel Laureate Charles Richet discovered over a hundred years ago that
injecting proteins into mammals can cause them to develop an allergy to
that protein.
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1913/richet-lecture.html
The US Dept. of Health and Human Services (HHS) charged the Institute of
Medicine (IOM) with providing a thorough review of the current medical
and scientific evidence on vaccines and vaccine adverse events.
The IOM has concluded in its 2011 report that:
FOOD PROTEINS PRESENT IN VACCINES CAUSE THE DEVELOPMENT OF FOOD ALLERGIES.
https://iom.nationalacademies.org/Reports/2011/Adverse-Effects-of-Vaccines-Evidence-and-Causality.aspx
Document Pg. 65 (pdf pg. 94 ):
“Adverse events on our list thought to be due to IgE-mediated
hypersensitivity reactions
Antigens in the vaccines that the committee is charged with reviewing do
not typically elicit an immediate hypersensitivity reaction (e.g.,
hepatitis B surface antigen, toxoids, gelatin, ovalbumin, casamino acids).
However, as will be discussed in subsequent chapters, the
above-mentioned antigens do occasionally induce IgE-mediated
sensitization in some individuals and subsequent hypersensitivity
reactions, including anaphylaxis."
For those who may not be familiar, here are the basics of allergy - a
two step process:
Sensitization: When exposure to an allergen (food protein) occurs for
the first time, there are no symptoms. Over a period of a few weeks, the
immune system develops antibodies specific to the allergen. The person
is now sensitized. In other words, the person has developed allergy to
the specific food item. “IgE-mediated sensitization”, is the technical
description for development of allergy.
Elicitation: When a sensitized person is exposed to the same allergen
again, they develop an immediate reaction (usually within minutes). Also
called hypersensitivity reaction. This is called elicitation. A severe,
life-threatening case of elicitation is known as anaphylaxis.
So in simple English, the IOM committee has concluded that food proteins
such as gelatin, egg (ovalbumin) and milk (casamino acid is derived from
milk) that are present in vaccines, cause healthy non-allergic people to
develop allergies to those food items upon receiving the vaccine.
In 2002, the doctors from the CDC and FDA warned that gelatin-containing
vaccines can cause gelatin allergy based on similar findings in Japan.
“Nonetheless, our cases with anti-gelatin IgE required some previous
exposure to gelatin to become sensitized, and this may have come through
ingestion of gelatin-containing food or injection of gelatin-containing
vaccines.”
They wrote: “Efforts should continue to identify less allergenic
substitutes for gelatin currently used by vaccine manufacturers.”.
Authors:
Vitali Pool, MD, CDC, M. Miles Braun, MD, MPH, FDA, John M. Kelso, MD,
Naval Medical Center, Gina Mootrey, DO, MPH, CDC, Robert T. Chen, MD,
MA, CDC, John W. Yunginger, MD, Robert M. Jacobson, MD, Mayo Clinic,
Paul M. Gargiullo, PhD, CD.
Prevalence of Anti-Gelatin IgE Antibodies in People With Anaphylaxis
After Measles-Mumps-Rubella Vaccine in the United States
http://pediatrics.aappublications.org/content/110/6/e71.long
Yet today, the CDC table here lists numerous food proteins contained in
vaccines, including gelatin, egg, milk (casamino acid), soy, seaweed (agar) and vegetable oils
(in Polysorbate 80, sorbitol).
http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
The result - the food allergy epidemic.
And gelatin in vaccines is still making kids sick today:
http://acaai.org/resources/connect/ask-allergist/Vaccines
Japan removed gelatin from their vaccines in 2000.
Kuno-Sakai H, Kimura M. Removal of gelatin from live vaccines and DTaP-an ultimate solution for vaccine-related gelatin allergy.Biologicals 2003;31:245-9
My son developed multiple life-threatening food allergies from these
food protein contaminated vaccines.
How can this situation ever be justified?
Vaccines are among the greatest achievements of modern medicine.
Food protein contaminated vaccines causing food allergy, is one of the worst blunders of modern medicine.

Has anyone done a scientific survey of people who have not been vaccinated compared with those who have been?
This could be yet another post hoc ergo propter hoc fallacy. Most children in the Western world have been vaccinated and many have allergies. It’s irresponsible to assume the vaccinations are causing the allergies without objective evidence, especially when vaccination is almost universal.
Lois

LoisL,
The IOM looked at ALL the scientific studies available from 1950s on this matter, for this report. There are many studies involving unvaccinated subjects in the IOM’s references. The IOM’s conclusion is based on the ENTIRE body of scientific evidence available on the subject.
If you noticed, the list of antigens in vaccines to which people are sensitized not only include food proteins but also include viral and bacterial proteins as well. So the IOM’s conclusion covers a much broader area than food allergies alone.

APV this seems to be an annual routine for you as you posted nearly the same thing about a year ago. The fact that vaccines can cause allergic reactions on rare occasions is no surprise. The very purpose of a vaccine is after all to illicit an immune response.
When looked at in aggregate though the number of allergic reactions caused by vaccines is extremely low. In regards to food allergies it is unclear, and the IOM report does not address, what proportion of food allergies if any vaccines might be responsible for. It has to be kept in mind that introduction of food proteins by any route including orally can induce an immune response so its likely that the majority of food allergies would still occur even if vaccines were entirely eliminated
It would of course be preferable if we could have vaccines ( and this is true of all medical interventions) that had no potential for adverse events. That will unfortunately never occur due to the the fact that every one of us is different in both genetic, epigenetic, and environmental factors. What has to be decided is whether the cost (in money and human suffering) of these adverse events warrants the effort and cost (including the use of funds and talent that could be used to solve other problems) of improving the existing vaccines. I’m not sure the problem you are referring to rises to the level that this is warranted but that is for others to decide.

macgyver,
“It has to be kept in mind that introduction of food proteins by any route including orally can induce an immune response”
That is not accurate for a normal healthy person with no medical intervention.
Exposure via oral route PRODUCES TOLERANCE NOT ALLERGY. Demonstrated here:
http://www.nejm.org/doi/full/10.1056/NEJMoa1414850
and here:
“The phenomenon of oral tolerance was first described by Wells and Osborne in 1911.5,6 They used guinea pigs to show that inclusion of egg white, purified egg allergens, or oats in the diet rendered the animals hyporesponsive to sensitization and anaphylaxis to those proteins. "
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807570/
If you are taking acid-reducing medication, then sensitization via oral route becomes likely because , we are interfering with protein digestion.
“what proportion of food allergies if
any vaccines might be responsible for.”
http://www.jacionline.org/article/S0091-6749(99)70508-7/abstract
2 out of 100 developed allergey to gelatin in the vaccine.
If you account for the various food allergens in vaccines, the 6-8% food allergy prevalence rate can be easily explained.
The IOM report found every vaccine causes anaphylaxis.
The paper above shows that sensitization needs less (typically 5X less ) allergen than elicitation (anaphylaxis).
So every vaccine has MORE THAN ENOUGH allergen to sensitize. Further, vaccines are administered up to 5 shots to a sitting. Many of them contain adjuvants such as aluminum salts and pertussis toxin that bias for allergy. Taken together, this makes vaccines very efficient at food allergy development.
If vaccines causing food allergy is well known in the medical community:

  1. There should be warning of vaccines causing food allergy in vaccine package inserts
  2. Food allergy should be on the vaccine injury table of the Vaccine Injury Compensation Program.
    Neither of the above is true and the medical community view (with the exception of the IOM) seems to be “we don’t know” what causes food allergy.

Your claim that oral exposure to allergens can not induce sensitivity is not accurate. While its true that the gut is an important part of our immune system and plays a critical role in creating tolerance to the myriad proteins we are exposed to every day the system is not perfect.
Brown Norway rat model of food allergy: Effect of plant components on the development of oral sensitization]
Many food allergies are likely due to errors and flaws in the complex series of steps required to create tolerance to all of these ingested proteins. No doubt genetics plays an important role in the failure to develop tolerance but the gut microbiome and diet are also likely to be important factors. The use of acid reducing agents is not a prerequisite for sensitivity to develop from oral exposure to proteins.
In regards to your request that “There should be warning of vaccines causing food allergy in vaccine package inserts”, there already is. If you look at the official MMR Vaccine Information Sheet] that physicians are required to make available to all patients when vaccines are provided (and which is available in multiple places on the internet]) you will see this statement “A vaccine, like any medicine, is capable of causing serious problems, such as severe allergic reactions.” The same warning is on the VIS for all vaccines.
Putting food allergies on the vaccine injury table of the Vaccine Injury Compensation Program would add cost to the health system since the program is funded by a tax on every dose of vaccine given. This would be passed on to patients and would end up mostly compensating people who were not injured by vaccines.
I am not saying that vaccines couldn’t be playing some role in food allergies but they are clearly not the sole cause and maybe not even an important cause. Their exact contribution is not clear by any means and the IOM report does not claim that they are.
The bottom line is that vaccines save a lot of lives. Avoiding them may possibly eliminate some undetermined percentage of food allergies but at what cost? We would return to a time when large numbers of people, especially children would die from Vaccine preventable diseases. So what is it that you are suggesting we do? The warnings are already on the package and compensation isn’t really going to do much to help kids who may or may not have been injured by vaccines. If you are suggesting that we do more research to find a way to produce vaccines without any antigens at all then you need to explain why this research is more deserving than the other research projects we are already spending our limited funds on and convince the powers that be that you are right.

macgyver,
“Brown Norway rat model of food allergy: Effect of plant components on the development of oral sensitization”
They injected carageenan as adjuvant to promote IgE (allergy). They also administered Gypsophila sp. saponin. So the sensitization did not occur naturally. The researchers defeated the natural processes to induce allergy for experimental reasons. How is this applicable to normal human beings?
“Many food allergies are likely due to errors and flaws in the complex series of steps required to create tolerance to all of these ingested proteins.”
But why does this happen only in developed countries in the last few decades only?
“A vaccine, like any medicine, is capable of causing serious problems, such as severe allergic reactions."
No. That is for ALREADY allergic (sensitized) people reacting to allergens in the vaccine.
There in NO warning that healthy people can develop an allergy anew, due to the food protein contaminated vaccine.
“vaccine injury table”
No amount of money can compensate a vaccine injured kid. Right now, vaccines injure kids (food allergy) with impunity. If a cost were associated with it, the hope is that it will be a deterrent to the ongoing injury of kids with unsafe vaccines.
“I am not saying that vaccines couldn’t be playing some role in food allergies but they are clearly not the sole cause and maybe not even an important cause.”
There is very little evidence that other routes like oral are the cause. The strongest demonstrated evidence is vaccines/injections causing them. As I wrote before, the IOM report lists food antigens ALONG with viral and bacterial proteins on the same list. There are numerous reports of sensitization to injected bacterial and viral proteins which were also the basis for IOM’s conclusion. So sensitization to injected proteins (food or viral) is a broad and well documented concept. The IOM report is the latest and most authoritative confirmation of Nobel Laureate Charles Richet’s discovery over a hundred years ago.
“If you are suggesting that we do more research to find a way to produce vaccines without any antigens at all”
Yes, without food antigens.
You are a doctor. Are you happy with 6-8% of your patients developing life-threatening food allergies to the vaccines you administer? Don’t you think that needs to be fixed?
Do you follow your patients health for a few months after each vaccine and report their food allergy diagnosis to the VAERS? I suspect most doctors don’t because it is not a documented side effect. So the problem will never be studied properly.
Japan removed gelatin from vaccines in 2000. Many vaccines are made without Polysorbate 80. While others contain Polysorbate 80 that is contaminated with various food proteins.
This shows we have the technology to produce food protein free vaccines. Unfortunately, it looks like it will cost lives lost to food allergy, millions of kids suffering food allergy and we still have to fight to make it happen …
The purpose of this post is to get support from professionals such as yourself to fix this unacceptable situation. Hope you will help.

My article in Frontiers in Basic Immunology 2015
Evidence that Food Proteins in Vaccines Cause the Development of Food
Allergies and its Implications for Vaccine Policy
https://mttmblog.files.wordpress.com/2015/10/frontiersabstractbk.pdf
Please see pg. 12.

This is simply a repetition of your previous claims presented as a poster. No data or evidence provided, no peer review, simply the same opinions expressed in a different format.

I am glad to see people who are concerned about people. Medicine is way above my comprehension level. So thank you for handling and talking about these difficult and very important issues.
There has to be some truth to these studies. And the affects may be different to different races depending on genes. The stem cell research may become the foundation for most of these types of studies in how they affect the human in the future. We may reach a point where vaccines will be custom made for the medical patient. For me, I am not going to be around long enough to worry about it. But I will still avoid stuff like Christmas shopping in large crowds.
My question is, do you think the support you are after might come for the area of the stem cell researchers?

mckenzievmd,
“no peer review”
Are you kidding? Not one but accepted by two independent panel of reviewers.

  1. Frontiers in Basic Immunology 2015
    Evidence that Food Proteins in Vaccines Cause the Development of Food
    Allergies and its Implications for Vaccine Policy
    https://mttmblog.files.wordpress.com/2015/10/frontiersabstractbk.pdf
    Please see pg. 12.
  2. Arumugham V (2015) Evidence that Food Proteins in Vaccines Cause the
    Development of Food Allergies and Its Implications for Vaccine Policy. J
    Develop Drugs
    4: 137. doi:10.4172/2329-6631.1000137
    http://www.omicsgroup.org/journals/evidence-that-food-proteins-in-vaccines-cause-the-development-of-foodallergies-and-its-implications-for-vaccine-policy-2329-6631-1000137.pdf

Wow! Thank you doctor (what were you medical credentials again?) for explaining to me how I happen to have so many food allergies after ingesting the foods…you know…orally. Do you know how (few) proteins are actually in each vaccine? And then there is that whole causation/correlation inconvenience… for example, everyone who breathes dies. True story. Stop breathing…

asanta,
Ingesting food proteins induces tolerance, not allergy.
http://www.nejm.org/doi/full/10.1056/NEJMoa1414850
If you read carefully and understand my paper, the rest of your questions will be answered.

asanta, Ingesting food proteins induces tolerance, not allergy. http://www.nejm.org/doi/full/10.1056/NEJMoa1414850 If you read carefully and *understand* my paper, the rest of your questions will be answered.
Yes, but I have allergies from ingestion. I have no tolerance for the things I am allergic to. They will kill me. Try to tell that to someone with a peanut allergy.

asanta,
Sorry to hear about your allergies.
If you were on anti-ulcer medication, it is possible to develop allergy by ingestion because the body’s natural protein processing is defeated by the medication.
The same is true for vaccines/injections because they bypass the natural protein processing in the stomach.
Order matters of course. If you were sensitized by a vaccine first, you cannot eat that protein (in normal doses) to gain tolerance.
If you ate the protein before being sensitized, you build tolerance.