If life evolved from a single cell, by descent with modification through natural selection, to the complexity and diversity we have today and throughout history, we can conclude it was the product of a slow accumulation of genetic mutations. Neutral genetic mutations are not relevant to this example, for they are neither detrimental, useful nor beneficial. Descent with modifications through Natural Selection dictates an accumulation of minute physical mutations over time. Every episode of a physical mutation is accompanied by a multiple of rejects. There would have been millions upon millions of physical mutations since the first cell. Based on science [observation and experiment] physical mutations are highly detrimental to living beings. 99% detrimental is a conservative number. Logically we can conclude that with every physical mutation, since the beginning of life, there was a 1% chance of life continuing. Following NS and science to a logical conclusion, billions upon billions of mutations should have extinguished life. The odds are highly against any successful accumulation of good variations that leads to a beneficial mutation. This is equivalent to continue rolling the same one hundred side dice and landing on the same number. Unguided natural forces could not achieve that level of repeatable effects. The dice is obviously loaded.
Use the heart, for example, specific material, shapes, dimensions, locations, etc. are needed for a good variation, and without very specific variations, the heart will not evolve into a functional heart. This is true for every part of the body, of any creature. Descent with modification through NS is the cause, a heart evolving is the effect. When the cause continues to produce the same effect despite the overwhelming odds against it, one has to question if the equation was rigged to continue to get the same result.
When the same cause brings about the same effect, over and over again, even though the probability is against it, it is teleological. This is because Natural Selection is ordered towards the same purpose, reproduction, and survival. Despite the odds of mutations surviving, new generations have continued to come into existence. Logically Natural Selection is teleological and therefore self-contradicting.