Am generally optimistic about things in life, but multidisciplinary science (e.g., Astrobiology) unfortunately attracted a lot of mediocrities/misfits/mavericks to the field over the past 20yrs or so, and consequently a fair amount of junk science has ended up being published. Cross-disciplinary work is certainly exciting & intellectually stimulating, but one has to have a good team of complementary expertises who can get along with one another in order to be able to make solid progress.